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Yt antigen system
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Yt_antigen_system" .
The Yt antigen system (also known as Cartwright ) is present on the membrane of red blood cells and helps determine a person's blood type . The antigens are found on the protein acetylcholinesterase , an enzyme which helps break down acetylcholine .[1] The Yt system features two alleles, Yt(a) and Yt(b). Antibodies against the Yt system can lead to transfusion reactions such as hemolytic anemia .
References
Online 'Mendelian Inheritance in Man' (OMIM) 112100 - OMIM page on Yt antigen
^ Bartels CF, Zelinski T, Lockridge O. Mutation at codon 322 in the human acetylcholinesterase (ACHE) gene accounts for YT blood group polymorphism. Am J Hum Genet. 1993 May;52(5):928-36. PMID 8488842
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