Whyte, from an upper middle class background, showed an early interest in writing, economics and social reform. After graduating from Swarthmore College, he was selected for the Junior Fellows program, where his landmark research was done. After his research in Boston, he entered the sociology doctoral program at the University of Chicago. Street Corner Society was published by the University of Chicago Press in 1943. He spent a year teaching at the University of Oklahoma, but developed polio in 1943 and spent two years in physical therapy at the Warm Springs Foundation. Rehabilitation was only partially successful; Whyte walked with a cane for the rest of his life, and using two arm crutches in his later years.
William Foote Whyte, Street Corner Society: The Social Structure of an Italian Slum University of Chicago Press (4th edition, 1993), trade paperback, ISBN 0-226-89545-9; hardcover, University of Chicago Press (3rd edition, revised and expanded, 1981, ISBN 0-226-89542-4; earlier editions available on ABE
William Foote Whyte, Participant Observer: An Autobiography, Cornell University Press (1994), trade paperback, ISBN 0-87546-325-8
William Foote Whyte, Creative Problem Solving in the Field: Reflections on a Career, Rowman and Littlefield (1997), trade paperback, ISBN 0-7619-8921-8; hardcover, ISBN 0-7619-8920-X
William Foote Whyte & Kathleen King Whyte, Making Mondragon: The Growth and Dynamics of the Worker Cooperative Complex, ILR Press (an imprint of Cornell University Press), Ithaca & London, 1988, ISBN 0-87546-182-4