The Varkud satellite (VS) ribozyme is an RNAenzyme that carries out the cleavage of a phosphodiester bond 1.
Structure
The VS ribozyme is composed of 5 helices that form an H shape (helices II to VI). The first helix (I) contains the substrate cleavage site in the stem-loop.
Species Distribution
The VS ribozyme has only been found in DNA of Neurospora mitochondria.
References
^ Saville BJ, Collins RA (1990). "A site-specific self-cleavage reaction performed by a novel RNA in Neurospora mitochondria". Cell61 (4): 685–696. doi:10.1016/0092-8674(90)90480-3.