U.S. Route 412 is an east-west United States highway, first commissioned in 1982. Its route number is a "violation" of the usual AASHTO numbering scheme, as it comes nowhere near its implied "parent", US 12. U.S. 412 overlaps expressway-grade Cimarron Turnpike from Tulsa west to Interstate 35 and the Cherokee Turnpike from 5 miles west of Chouteau, Oklahoma, to 8 miles west of the Arkansas state line. U.S. 412 has a bannered route in eastern Oklahoma named Scenic US 412, one of only two such routes in the country. Another curiosity of this highway is that it runs the entire length of the Oklahoma Panhandle and traverses the Missouri Bootheel.
The Arkansas section runs through the scenic Ozark Mountains starting at the Oklahoma line and runs through the northern part of Arkansas exiting the state at the Missouri boot heel. Cities along the route include Siloam Springs, Springdale, Alpena, Harrison, Cotter, Mountain Home, Salem, Walnut Ridge, and Paragould. Just east of Mountain Home, in Henderson, the highway crosses Lake Norfork, which at one time had to be crossed by ferry. The finial trip of a Norfork Lake ferry at 8 a.m. Friday, October 24, 1958, the U.S. Highway 62 bridge across Lake Norfork was opened, about the same time the last official ferry crossing was made. Charles Gibson piloted that ferry, carrying three cars across the lake within the shadow of the bridge which brought a 40-year era to an end.4
Missouri
U.S. Route 412 crosses Missouri on its bootheel, making it cross four states along its journey.
Tennessee
Business U.S. Highway 412 turns right in Jackson, Tennessee.
The section from I-65 near Columbia westbound is overlapped with unsignedTennessee State Route 99. East of I-65 at the eastern terminus of US 412, the route remains Tennessee 99.