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Tubulin, alpha 8
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| PDB rendering based on 1tub. | ||||||||||||||
| Available structures: 1tub, 1tvk, 1z2b | ||||||||||||||
| Identifiers | ||||||||||||||
| Symbols | TUBA8; TUBAL2 | |||||||||||||
| External IDs | OMIM: 605742 MGI: 1858225 HomoloGene: 56766 | |||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 51807 | 53857 | ||||||||||||
| Ensembl | n/a | ENSMUSG00000030137 | ||||||||||||
| Uniprot | n/a | Q9JJZ2 | ||||||||||||
| Refseq | NM_018943 (mRNA) NP_061816 (protein) |
NM_017379 (mRNA) NP_059075 (protein) |
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| Location | n/a | Chr 6: 121.19 - 121.19 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Tubulin, alpha 8, also known as TUBA8, is a human gene.[1]
References
Further reading
- Alexandrova N, Niklinski J, Bliskovsky V, et al. (1995). "The N-terminal domain of c-Myc associates with alpha-tubulin and microtubules in vivo and in vitro.". Mol. Cell. Biol. 15 (9): 5188–95. PMID 7651436.
- Feierbach B, Nogales E, Downing KH, Stearns T (1999). "Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin.". J. Cell Biol. 144 (1): 113–24. PMID 9885248.
- Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22.". Nature 402 (6761): 489–95. doi:. PMID 10591208.
- Stanchi F, Corso V, Scannapieco P, et al. (2000). "TUBA8: A new tissue-specific isoform of alpha-tubulin that is highly conserved in human and mouse.". Biochem. Biophys. Res. Commun. 270 (3): 1111–8. doi:. PMID 10772959.
- Herreros L, Rodríguez-Fernandez JL, Brown MC, et al. (2000). "Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton.". J. Biol. Chem. 275 (34): 26436–40. doi:. PMID 10840040.
- Watts NR, Sackett DL, Ward RD, et al. (2000). "HIV-1 rev depolymerizes microtubules to form stable bilayered rings.". J. Cell Biol. 150 (2): 349–60. PMID 10908577.
- Germani A, Bruzzoni-Giovanelli H, Fellous A, et al. (2001). "SIAH-1 interacts with alpha-tubulin and degrades the kinesin Kid by the proteasome pathway during mitosis.". Oncogene 19 (52): 5997–6006. doi:. PMID 11146551.
- Saugstad JA, Yang S, Pohl J, et al. (2002). "Interaction between metabotropic glutamate receptor 7 and alpha tubulin.". J. Neurochem. 80 (6): 980–8. PMID 11953448.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:. PMID 12477932.
- Chen D, Wang M, Zhou S, Zhou Q (2004). "HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim.". EMBO J. 21 (24): 6801–10. PMID 12486001.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:. PMID 14702039.
- Xu Y, Kulkosky J, Acheampong E, et al. (2004). "HIV-1-mediated apoptosis of neuronal cells: Proximal molecular mechanisms of HIV-1-induced encephalopathy.". Proc. Natl. Acad. Sci. U.S.A. 101 (18): 7070–5. doi:. PMID 15103018.
- Campbell GR, Pasquier E, Watkins J, et al. (2005). "The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis.". J. Biol. Chem. 279 (46): 48197–204. doi:. PMID 15331610.
- Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome.". Genome Biol. 5 (10): R84. doi:. PMID 15461802.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:. PMID 15489334.
- de Mareuil J, Carre M, Barbier P, et al. (2006). "HIV-1 Tat protein enhances microtubule polymerization.". Retrovirology 2: 5. doi:. PMID 15691386.
- Giacca M (2006). "HIV-1 Tat, apoptosis and the mitochondria: a tubulin link?". Retrovirology 2: 7. doi:. PMID 15698476.
- Valenzuela-Fernández A, Alvarez S, Gordon-Alonso M, et al. (2006). "Histone deacetylase 6 regulates human immunodeficiency virus type 1 infection.". Mol. Biol. Cell 16 (11): 5445–54. doi:. PMID 16148047.
- Canani RB, De Marco G, Passariello A, et al. (2006). "Inhibitory effect of HIV-1 Tat protein on the sodium-D-glucose symporter of human intestinal epithelial cells.". AIDS 20 (1): 5–10. PMID 16327313.
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