Spermidine
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Spermidine
IUPAC name	N-(3-aminopropyl)butane-1,4-diamine
Other names	1,5,10-triazadecane
Identifiers
CAS number	[124-20-9]
PubChem	1102
MeSH	Spermidine
SMILES	C(CCNCCCN)CN
Properties
Molecular formula	C7H19N3
Molar mass	145.246
Density	0.925 g/mL at 25 °C
Melting point	22-25.0 °C
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references

Spermidine is a polyamine involved in cellular metabolism that can be used to stimulate the enzyme, T7 RNA polymerase, a type of RNA polymerase.

Biochemical actions

• Inhibits neuronal nitric oxide synthase (nNOS).
• Binds and precipitates DNA.
• May be used for purification of DNA binding proteins.
• Stimulates T4 polynucleotide kinase activity.

Some of the uses

• Can be used in electroporation while transfering the DNA into the cell under the electrical impulse.

Safety

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

See also

• Spermine
• Putrescine

External links

• Safety Data Sheet

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