The area, comprising what is now known as the Louisiana Purchase, was turned over to the French for a few days in 1803 before it, in turn, was turned over to the United States.
Spain was to be largely a benign absentee landlord administering it from Havana, Cuba and contracting out governing to people from many nationalities as long as they swore allegiance to Spain.
Although only maintaining it for 36 years, the Spanish were the ones who in fact were responsible for establishing much of New Orleans and Louisiana character that are normally associated with the French. Further, the Spanish control was to continue Catholic influence in the region.
1714 - Natchitoches Established by Louis Juchereau de St. Denis as part of French Louisiana, the community was named after the Natchitoches Indian tribe. The City of Natchitoches was first incorporated on February 5, 1819. It is the oldest permanent settlement in the Louisiana Purchase.
1763 - Treaty of Paris (1763) ends the war with a provision in which France cedes all territory east of the Mississippi (including French Canada) to Britain. Spain cedes Florida and land east of the Mississippi (including Baton Rouge, Louisiana to Britain.
1763 - The Cajun migration begins with French settlers from Quebec and settlers on the east side of the Mississippi who had been ordered to leave from the new Native American migrating to Louisiana which they believe is still French controlled land west of the Mississippi as well as New Orleans
1764 - Formal announcement that Spain has acquired Louisiana
1768 - Antonio de Ulloa becomes the first Spanish governor of Louisiana. He does not fly the Spanish flag and is run off by a pro-French mob in the Rebellion of 1768
1769 - Alejandro O'Reilly suppresses the rebellion, executes its leaders and sends other plotters to prison in Morro Castle (fortress) in Havana. He establishes Spanish law and the cabildo of New Orleans. However he is otherwise benign and forgives other plotters as long as they swear allegiance to Spain.
1770 - Luis de Unzaga starts the era of benign Spanish rule and frees the imprisoned plotters
1770 - Spain begins an administrative of process of governing Upper Louisiana with lieutenant governors
1789 - Work on rebuilding New Orleans including what is now the French Quarter begins. The new structures have courtyards and stone walls. The cornersone for the new St. Louis Cathedral, New Orleans laid.
1795 - Pinckney's Treaty settles boundary disputes with the United States and recognizes rights to navigate through New Orleans
1803 - Announcement of Louisiana Purchase by United States
1803 - Spain refuses Lewis and Clark permission to travel up Missouri River since the transfer from France has never been made official. They spend winter in Illinois at Camp Dubois
1804 - France officially takes control in December 1803 but word is not conveyed to St. Louis until 1804 at Three Flags Day