The highest point is probably Cerro Mohinora, located at 25°57′N, 107°03′W. Different sources cite its altitude as either 3250 m or 3300 m. However, other mountains at 26°03′N, 106°25′W and 23°12′N, 104°57′W are of very similar altitude and may possibly be higher.
The mountains are home to several indigenous nations speaking Uto-Aztecan languages, including the Tarahumara in the central portion of the range, and the Huichol in the southern part of the range.