Sick-euthyroid syndrome

Sick-euthyroid syndrome
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Sick-euthyroid_syndrome".

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Euthyroid sick syndrome Classification and external resources
ICD-10	E 07.8
ICD-9	790.94
eMedicine	med/753
MeSH	D005067

Euthyroid sick syndrome is a thyroid hormone disorder where the levels of T3 and/or T4 are at unusual levels, but the thyroid gland does not appear to be dysfunctional.

Causes

Fasting, starvation, sepsis, trauma, cardiopulmonary bypass, malignancy, heart failure, hypothermia, myocardial infarction, chronic renal failure, cirrhosis, and diabetic ketoacidosis.

Diagnosis

Ill patients may have normal to low TSH depending on the spectrum of illness. Total T4 and T3 levels may be altered by binding protein abnormalities, and medications. Reverse T3 are generally increased signifying inhibition of normal Type 1 enzyme or reduced clearance of reverse T3. Measurement of free T4 and/or free T3 levels will be normal.

External links

McIver B, Gorman C (1997). "Euthyroid sick syndrome: an overview". Thyroid 7 (1): 125–32. PMID 9086580.
Overview at vghtc.gov.tw
Overview at merck.com

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v • d • e

Endocrine pathology: endocrine diseases (E00-35, 240-259)

Pancreas/
glucose
metabolism

Diabetes mellitus types: (type 1, type 2, MODY), complications: (coma, angiopathy, ketoacidosis, nephropathy, neuropathy, retinopathy)
Hypoglycemia - Hyperinsulinism - Zollinger-Ellison syndrome - insulin receptor (Rabson-Mendenhall syndrome) - Insulin resistance

H/P axes

Pituitary	Hyperpituitarism (Acromegaly, Hyperprolactinaemia, SIADH) Hypopituitarism (Sheehan's syndrome, Kallmann syndrome, Growth hormone deficiency, Diabetes insipidus) Adiposogenital dystrophy - Empty sella syndrome - Pituitary apoplexy - ACTH deficiency

Thyroid	Hypothyroidism (Iodine deficiency, Cretinism, Congenital hypothyroidism, Goitre, Myxedema) Hyperthyroidism (Graves disease, Toxic multinodular goitre, Teratoma with thyroid tissue or Struma ovarii) Thyroiditis (De Quervain's thyroiditis, Hashimoto's thyroiditis, Riedel's thyroiditis) Euthyroid sick syndrome - Thyroid hormone resistance - Thyroid nodule

Parathyroid	Hypoparathyroidism (Pseudohypoparathyroidism) - Hyperparathyroidism (Primary, Secondary, Tertiary)

Adrenal	Adrenocortical hyperfunction: Cushing's syndrome (Nelson's syndrome, Pseudo-Cushing's syndrome) - Hyperaldosteronism (Conn syndrome, Bartter syndrome) CAH (Lipoid, 3β, 11β, 17α, 21α) Adrenal insufficiency (Addison's disease, Waterhouse-Friderichsen syndrome) - Hypoaldosteronism

Gonads	ovarian (Polycystic ovary syndrome, Premature ovarian failure) testicular (5-alpha-reductase deficiency, 17-beta-hydroxysteroid dehydrogenase deficiency) general (Hypogonadism, Delayed puberty, Precocious puberty)

Other

Androgen insensitivity syndrome - Autoimmune polyendocrine syndrome - Carcinoid syndrome - Gigantism - Short stature (Laron syndrome, Psychogenic dwarfism) - Multiple endocrine neoplasia (1, 2) - Progeria - Woodhouse-Sakati syndrome - thymus (Abscess of thymus, Thymus hyperplasia)

see also congenital, neoplasia

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