In 1999, he resigned once again to run for the Duma, and was elected again as a Communist. This time, however, he clashed with the party's leadership and, in 2003, he abandoned the party to help form Rodina, a populist, nationalist party on the left wing of the Russian political spectrum. That year, he became one of 37 Rodina candidates elected to the Duma. Other prominent candidates included Dmitry Rogozin, Chairman of the Duman Foreign Affairs Committee and co-chairman (with Glazyev) of Rodina, and also former Central Bank head Viktor Gerashchenko.
In 2004, both Glazyev and Gerashchenko sought the presidency on separate tickets, with Rodina's leaders voting to remain neutral in the contest. Gerashchenko was nominated as the candidate of one of the minor parties that made up the Rodina coalition, which led to the Central Election Commission refusing to place him on the ballot, as he had not been nominated by the whole party. Glazyev, who had nominated himself as an Independent, did not have any such problems, and appeared on the ballot.
Following the election, Rogozin, who had long sought to remove his rival from party power, succeeded in getting the party rank-and-file to vote Glazyev out as co-chairman, leaving Rogozin in control. This led to Glazyev and his supporters attempting to form their own party, called For a Decent Life, although this, too, suffered a setback when the Ministry of Justice refused to recognize the validity of the party.
Glazyev announced his retirement from politics in March 2007, and said that he did not intend to seek a further term in the Duma, arguing that Vladimir Putin's rule had crowded out all forms of political opposition and debate in the country.
Glazyev has authored more than forty books and hundreds of pamphlets and research papers. One of his books has been published in English translation by the LaRouche movement's Executive Intelligence Review as Genocide: Russia and the New World Order (ISBN 0-943235-16-2).