Saône-et-Loire is the seventh largest department of France and the most densely populated in the region of Bourgogne. In the west the department is composed of the hills of the Autunois, the region around Autun, of the Charollais and of the Mâconnais. In the center it is traversed from north to south by the Saône in its wide plain; the Saône is a tributary of the River Rhône that joins it at Lyon and thus is connected to the Mediterranean Sea. The Loire makes its way in the opposite direction, draining into the Atlantic Ocean. The Canal du Centre links the Saône to the Loire between Chalon-sur-Saône and Digoin, thereby linking the Mediterranean Sea to the Atlantic ocean. In the east the department occupies the northern part of the plain of Bresse. In the west its industrial heart is in Le Creusot and Montceau-les-Mines.