The construction of this church was started in 1507 by Antonio da Sangallo the younger, with an octagonal floor plan; the dome and the lantern were completed by Jacopo del Duca some 75 years later. The church was built atop an earlier 15th century chapel. It is most notable for the adjacent erection of a similarly domed 18th century church Santissimo Nome di Maria, giving the semblance of twin churches.