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Serpin peptidase inhibitor, clade B (ovalbumin), member 1
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| Identifiers | |||||||||||
| Symbols | SERPINB1; EI; ELANH2; LEI; M/NEI; MNEI; PI2 | ||||||||||
| External IDs | OMIM: 130135 MGI: 1913472 HomoloGene: 69399 | ||||||||||
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| RNA expression pattern | |||||||||||
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| Orthologs | |||||||||||
| Human | Mouse | ||||||||||
| Entrez | 1992 | 66222 | |||||||||
| Ensembl | ENSG00000021355 | n/a | |||||||||
| Uniprot | P30740 | n/a | |||||||||
| Refseq | NM_030666 (mRNA) NP_109591 (protein) |
NM_025429 (mRNA) NP_079705 (protein) |
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| Location | Chr 6: 2.78 - 2.79 Mb | n/a | |||||||||
| Pubmed search | [1] | [2] | |||||||||
Serpin peptidase inhibitor, clade B (ovalbumin), member 1, also known as SERPINB1, is a human gene.[1]
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See also
References
Further reading
- Rasmussen HH, van Damme J, Puype M, et al. (1993). "Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes.". Electrophoresis 13 (12): 960–9. PMID 1286667.
- Remold-O'Donnell E, Chin J, Alberts M (1992). "Sequence and molecular characterization of human monocyte/neutrophil elastase inhibitor.". Proc. Natl. Acad. Sci. U.S.A. 89 (12): 5635–9. PMID 1376927.
- Packard BZ, Lee SS, Remold-O'Donnell E, Komoriya A (1995). "A serpin from human tumor cells with direct lymphoid immunomodulatory activity: mitogenic stimulation of human tumor-infiltrating lymphocytes.". Biochim. Biophys. Acta 1269 (1): 41–50. PMID 7578269.
- Sugimori T, Cooley J, Hoidal JR, Remold-O'Donnell E (1995). "Inhibitory properties of recombinant human monocyte/neutrophil elastase inhibitor.". Am. J. Respir. Cell Mol. Biol. 13 (3): 314–22. PMID 7654387.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
- Evans E, Cooley J, Remold-O'Donnell E (1996). "Characterization and chromosomal localization of ELANH2, the gene encoding human monocyte/neutrophil elastase inhibitor.". Genomics 28 (2): 235–40. doi:. PMID 8530031.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
- Zeng W, Silverman GA, Remold-O'Donnell E (1998). "Structure and sequence of human M/NEI (monocyte/neutrophil elastase inhibitor), an Ov-serpin family gene.". Gene 213 (1-2): 179–87. PMID 9630619.
- Sun J, Stephens R, Mirza G, et al. (1999). "A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes.". Cytogenet. Cell Genet. 82 (3-4): 273–7. PMID 9858835.
- Perani P, Zeggai S, Torriglia A, Courtois Y (2000). "Mutations on the hinge region of leukocyte elastase inhibitor determine the loss of inhibitory function.". Biochem. Biophys. Res. Commun. 274 (3): 841–4. doi:. PMID 10924364.
- Cooley J, Takayama TK, Shapiro SD, et al. (2002). "The serpin MNEI inhibits elastase-like and chymotrypsin-like serine proteases through efficient reactions at two active sites.". Biochemistry 40 (51): 15762–70. PMID 11747453.
- Korkmaz B, Attucci S, Hazouard E, et al. (2002). "Discriminating between the activities of human neutrophil elastase and proteinase 3 using serpin-derived fluorogenic substrates.". J. Biol. Chem. 277 (42): 39074–81. doi:. PMID 12114510.
- Benarafa C, Cooley J, Zeng W, et al. (2003). "Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1).". J. Biol. Chem. 277 (44): 42028–33. doi:. PMID 12189154.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:. PMID 12477932.
- Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.". Nat. Biotechnol. 21 (5): 566–9. doi:. PMID 12665801.
- Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. doi:. PMID 14574404.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:. PMID 15489334.
- Ahmed M, Forsberg J, Bergsten P (2005). "Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry.". J. Proteome Res. 4 (3): 931–40. doi:. PMID 15952740.
External links
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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