Pyrovalerone (Centroton, Thymergix) is a stimulant drug developed in the late 1960s and used in France and some other European countries. It is sometimes prescribed for treating chronic fatigue and lethargy[1] or as an appetite suppressant, though it is used infrequently due to problems with abuse and dependence.[2] Side effects of pyrovalerone include loss of appetite, anxiety, insomnia, and tremor. Withdrawal syndrome following abuse causes depression.[3] Pyrovalerone is a Schedule V drug in the USA.[4] It is closely related to some other stimulant drugs such as prolintane and MDPV.
^ Gardos G, Cole JO. Evaluation of pyrovalerone in chronically fatigued volunteers. Current Therapeutic Research, Clinical and Experimental. 1971 Oct;13(10):631-5.
^ Deniker P, Loo H, Cuche H, Roux JM. Abuse of pyrovalerone by drug addicts. Annales Medico-Psychologiques (Paris) 1975 Nov;2(4):745-8.
