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Phosphoglucoisomerase
Glucose-6-phosphate isomerase , or phosphoglucose isomerase , is an enzyme (EC 5.3.1.9 ) that catalyzes the conversion of glucose-6-phosphate into fructose-6-phosphate in the second step of glycolysis . An unrelated enzyme, D-xylose isomerase (EC 5.3.1.5 ) catalyzes the isomerization of glucose to fructose , and is sometimes called "glucose isomerase".
The human variant of this enzyme is encoded by the GPI gene .
In glycolysis Compound C00668 at KEGG Pathway Database. Enzyme 5.3.1.9 at KEGG Pathway Database. Compound C05345 at KEGG Pathway Database. Reaction R00771 at KEGG Pathway Database.
As a glucose isomerase
Other functions There is evidence that phosphoglucose isomerase acts as a molecular messenger. It is produced and secreted by white blood cells , and acts to regulate the growth of several different cell types.
