The Denys Wilkinson Building is a prominent 1960s building at the southern end of the Banbury Road in Oxford, England. It houses the astrophysics and particle physics departments at Oxford University. It was originally built for the then Department of Nuclear Physics and named the Nuclear Physics Laboratory. In 2001, the building was renamed as the Denys Wilkinson Building, in honour of the British nuclear physicist Sir Denys Wilkinson (born 1922), who was involved in its original creation.
The building is located on the corner of Banbury Road to the west and Keble Road to the south. Immediately to the north is the tall Thom Building of Oxford University's Department of Engineering Science, also built in the 1960s.
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