Nonce words frequently arise through the combination of an existing word with a familiar prefix or suffix, in order to meet a particular need (or as a joke). The result is a special kind of pseudoword: although it would not be found in any dictionary, it is instantly comprehensible (e.g., bananular phone). If the need recurs (or the joke is widely enjoyed), nonce words easily enter regular use (initially as neologisms) just because their meaning is obvious.
Slithy, as a portmanteau of "slimy" and "lithe"; chortle as a portmanteau of "chuckle" and "snort"; among several used by Lewis Carroll in Jabberwocky.
"Runcible spoon", from Edward Lear, which later came to describe a curved fork with a cutting edge.
Unidexter - a one-legged person of the right-legged persuasion. Coined by comedian Peter Cook in One Leg Too Few.
Surlecultant in French, meaning that gets you to sit down in a rather vulgar manner. A rough translation would be 'onto-the-arse-ing'.
Contrafibularatories was one of several nonce words used by the fictional Edmund Blackadder to confuse the lexicographerSamuel Johnson, whom Blackadder despised. Among the others were anaspeptic, phrasmotic, periconbobulations, interphrastically and extramuralization.
Kwyjibo used in The Simpsons 'Bart the Genius' in a game of Scrabble, meaning "a bald, overweight, North American ape of below average intelligence".
Trubicle used in the greater Lexington, Kentucky area, meaning "a windowless workplace area that is surrounded by artificial walls, with an opening on one side (as opposed to a door). This structure is then occupied by three co-workers, usually with similar job responsibilities".