Mevalonate kinase

Mevalonate kinase
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Mevalonate_kinase".

content

mevalonate kinase (mevalonic aciduria)
Identifiers
Symbol	MVK
Entrez	4598
HUGO	7530
OMIM	251170
RefSeq	NM_000431
UniProt	Q03426
Other data
EC number	2.7.1.36
Locus	Chr. 12 q24

Mevalonate kinase is an enzyme in the mevalonate pathway.

See also

Mevalonate pathway

Mevalonate pathway

External links

MeSH mevalonate+kinase

This biochemistry article is a stub. You can help Wikipedia by expanding it.

v • d • e Transferases: Phosphotransferases/kinases (EC 2.7)

2.7.1 - OH acceptor	Hexo- - Gluco- - Fructo- (Hepatic fructo-) - Galacto- - Phosphofructo- (1, 2) - Riboflavin - Shikimate - Thymidine - NAD⁺ - Glycerol - Pantothenate - Mevalonate - Pyruvate - Deoxycytidine - PFP - Diacylglycerol - Bruton's tyrosine - Phosphoinositide 3 (Class I PI 3, Class II PI 3) - Sphingosine

2.7.2 - COOH acceptor	Phosphoglycerate - Aspartate

2.7.3 - N acceptor	Creatine

2.7.4 - PO₄ acceptor	Phosphomevalonate - Adenylate - Nucleoside-diphosphate

2.7.6 - P₂O₇	Ribose-phosphate diphosphokinase - Thiamine pyrophosphokinase

2.7.7 - nucleotidyl-	Integrase - PNPase - Polymerase - RNase PH - UDP-glucose pyrophosphorylase - Galactose-1-phosphate uridylyltransferase -Terminal deoxynucleotidyl transferase - RNA replicase - Reverse transcriptase (Telomerase) - Transposase

2.7.8 - other phos.	N-acetylglucosamine-1-phosphate transferase

2.7.10-11 - protein	Tyrosine - Serine/threonine-specific

v • d • e Metabolism: lipid metabolism - ketones/mevalonate pathway/cholesterol synthesis enzymes

To HMG-CoA	Acetyl-Coenzyme A acetyltransferase - HMG-CoA synthase (regulated step)

Ketogenesis	HMG-CoA lyase - 3-hydroxybutyrate dehydrogenase - Thiophorase

To Mevalonic acid	HMG-CoA reductase

To DMAPP	Mevalonate kinase - Phosphomevalonate kinase - Pyrophosphomevalonate decarboxylase - Isopentenyl-diphosphate delta isomerase

To Cholesterols	Dimethylallyltranstransferase - Geranyl pyrophosphate - Farnesyl-diphosphate farnesyltransferase - Squalene monooxygenase - Lanosterol synthase - CYP51A1

To Bile acids	Cholesterol 7 alpha-hydroxylase

see also intermediates

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