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| Luteolin | |
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| IUPAC name | 2-(3,4-Dihydroxyphenyl)- 5,7-dihydroxy-4-chromenone |
| Other names | Luteolol Digitoflavone Flacitran Luteoline |
| Identifiers | |
| CAS number | [491-70-3] |
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| Properties | |
| Molecular formula | C15H10O6 |
| Molar mass | 286.24 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references |
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Luteolin is a flavonoid; more specifically, it is one of the more common flavones.[1] It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an agent in the prevention of inflammation, a promoter of carbohydrate metabolism, and an immune system modulator. These characteristics of luteolin are also believed to play an important part in the prevention of cancer. Multiple research experiments describe luteolin as a biochemical agent that can dramatically reduce inflammation[2] and the symptoms of septic shock.
Luteolin is most often found in leaves, but it is also seen in rinds, barks, clover blossom and ragweed pollen.[1] It has also been isolated from Salvia tomentosa.[3] Dietary sources include celery, green pepper, perilla and camomile tea.[4]
References
- ^ a b Mann, John (1992). Secondary Metabolism (2nd. ed.). Oxford, UK: Oxford University Press, 279-280. ISBN 0-19-855529-6.
- ^ Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1 — PNAS
- ^ A. Ulubelen, M. Miski, P. Neuman, and T. J. Mabry (1979). "Flavonoids of Salvia tomentosa (Labiatae)". Journal of Natural Products 42 (4): 261–263. doi:.
- ^ Kayoko Shimoi, Hisae Okada, Michiyo Furugori, Toshinao Goda, Sachiko Takase, Masayuki Suzuki, Yukihiko Hara, Hiroyo Yamamoto, Naohide Kinae (1998). "Intestinal absorption of luteolin and luteolin 7-O-[beta]-glucoside in rats and humans". FEBS Letters 438 (3): 220–224. doi:.
