Kavner was born in Los Angeles, California, the daughter of Rose (née Bienstock), a family counselor, and David Kavner, a furniture manufacturer.2 She grew up entirely in Southern California, a fact that comes as a surprise to many people who identify her with her role as New Yorker Brenda Morgenstern and who peg her creaky, somewhat nasally voice as sounding "East Coast".citation needed Kavner went to Beverly Hills High School and studied Theater Arts, graduating with honors from San Diego State University in 1971. Her daughter was born in 1984.
In The Simpsons, Kavner provides the voices for Marge Simpson, Patty Bouvier, Selma Bouvier, Jacqueline Ingrid "Jackie" Bouvier and Gladys Bouvier.1 She has been knowncitation needed to refuse to perform any of her characters' voices in public. Kavner even goes as far as to not allow any film footage of her doing the characters from The Simpsons to be captured. The reason for this is because she contorts her face and doesn't want people to see it.citation needed She did however perform Marge's voice on Inside the Actor's Studio, but during the performance the television audience saw only clips of Marge from the series over her voice.1 To perform Marge's voice, Kavner raises her voice by about an octave, and roughens it up a bit; to do Patty and Selma, she lowers her voice an octave, and roughens it up a lot.citation needed
Series creator Matt Groening said, "My original idea about Marge's family was they were utterly joyless. The original note I gave to Julie was that they suck the life out of everything they see'".3