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JWH-018
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| Systematic (IUPAC) name | |
| naphthalen-1-yl-(1-pentylindol-3-yl)methanone | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C24H23NO |
| Mol. mass | 341.45 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status |
Legal |
| Routes | ? |
JWH-018 (1-Pentyl-3-(1-Naphthoyl)Indole) is an analgesic drug from the aminoalkylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors, with some selectivity for CB2.1 It produces effects in animals very similar to those of THC itself, but with a shorter duration of action, and is currently being researched as a potential analgesic to be administered by transdermal patch.2
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References
- ^ Aung MM, Griffin G, Huffman JW, Wu MJ, Keel C, Yang B, Showalter VM, Abood ME, Martin BR. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug and Alcohol Dependance 2000; 60:133-140.
- ^ Transdermal Delivery of Cannabinoids. WO/2007/001891
External links
