Isovaleryl coenzyme A dehydrogenase

content

isovaleryl Coenzyme A dehydrogenase
Identifiers
Symbol	IVD
Entrez	3712
HUGO	6186
OMIM	607036
RefSeq	NM_002225
UniProt	P26440
Other data
EC number	1.3.99.10
Locus	Chr. 15 q14-q15

Isovaleryl coenzyme A dehydrogenase is an enzyme which catalyzes the conversion of isovaleryl-coenzyme A to methylcrotonyl-CoA.

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v • d • e Oxidoreductases: CH-CH oxidoreductases (EC 1.3)

1.3.1. NAD/NADP acceptor	Enoyl-acyl carrier protein reductase/Enoyl ACP reductase - 7-Dehydrocholesterol reductase - Biliverdin reductase - 2,4 Dienoyl-CoA reductase

1.3.3. Oxygen acceptor	Dihydroorotate dehydrogenase - Coproporphyrinogen III oxidase - Protoporphyrinogen oxidase -

1.3.5. Quinone	Succinate dehydrogenase

1.3.99. Other acceptors	Fumarate reductase - Butyryl CoA dehydrogenase - Acyl CoA dehydrogenase (ACADSB) - 5-alpha reductase - Glutaryl-CoA dehydrogenase - Isovaleryl coenzyme A dehydrogenase

v • d • e

LYSINE→	Saccharopine dehydrogenase - Glutaryl-CoA dehydrogenase

LEUCINE→	Branched chain aminotransferase - Branched-chain alpha-keto acid dehydrogenase complex - Isovaleryl coenzyme A dehydrogenase - Methylcrotonyl-CoA carboxylase - Methylglutaconyl-CoA hydratase - 3-hydroxy-3-methylglutaryl-CoA lyase

TRYPTOPHAN→	Indoleamine 2,3-dioxygenase/Tryptophan 2,3-dioxygenase - Arylformamidase - Kynureninase - 3-hydroxyanthranilate oxidase - Aminocarboxymuconate-semialdehyde decarboxylase - Aminomuconate-semialdehyde dehydrogenase

PHENYLALANINE→tyrosine→	(see below)

glycine→serine→	Serine hydroxymethyltransferase - Serine dehydratase

alanine→	Alanine transaminase

cysteine→	D-cysteine desulfhydrase

threonine→	L-threonine dehydrogenase


HISTIDINE→	Histidine ammonia-lyase - Urocanate hydratase - Formiminotransferase cyclodeaminase

proline→	Proline oxidase - Pyrroline-5-carboxylate reductase - 1-Pyrroline-5-carboxylate dehydrogenase/ALDH4A1 - PYCR1

arginine→	Ornithine aminotransferase - Ornithine decarboxylase - Agmatinase

→alpha-ketoglutarate→TCA	Glutamate dehydrogenase


PHENYLALANINE→tyrosine→	Phenylalanine hydroxylase - Tyrosine aminotransferase - 4-Hydroxyphenylpyruvate dioxygenase - Homogentisate 1,2-dioxygenase - Fumarylacetoacetate hydrolase


asparagine→aspartate→	Asparaginase/Asparagine synthetase - Aspartate transaminase

Other

see also disorders, intermediates