Iron overload disorder
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Iron_overload_disorder".

In medicine, iron overload disorders are diseases caused by the accumulation of iron in the body. Organs commonly affected are the liver, heart and endocrine glands.^[1]

Causes

The causes can be distinguished between primary (generally genetic) and secondary (due to other conditions).^[2]

Primary iron overload

Secondary iron overload

• Dietary iron overload
• Transfusional iron overload
• Long term haemodialysis
• Chronic liver disease
  • Hepatitis C
  • Alcoholic cirrhosis, especially when advanced
  • Non-alcoholic steatohepatitis
• Porphyria cutanea tarda
• Post-portacaval shunting
• Dysmetabolic iron overload syndrome

Miscellaneous

The part-genetic, part-environmental syndrome known as African iron overload in sub-Sahara Africa (Online 'Mendelian Inheritance in Man' (OMIM) 601195)

See also

• Iron deficiency
• Siderosis
• Hemosiderosis
• Human iron metabolism

References

1. ^ Andrews NC (1999). "Disorders of iron metabolism". N. Engl. J. Med. 341 (26): 1986–95. doi:10.1056/NEJM199912233412607. PMID 10607817. 
2. ^ Pietrangelo A (2003). "Haemochromatosis". Gut 52 Suppl 2: ii23–30. PMID 12651879. 

External links

• Texas Medical Center
• Merck
• Iron Overload.org