Interleukin-22 receptor
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Interleukin-22_receptor".

content
interleukin 22 receptor, alpha 1
Identifiers
Symbol IL22RA1
Alt. Symbols IL22R
Entrez 58985
HUGO 13700
OMIM 605457
RefSeq NM_021258
UniProt A8K839
Other data
Locus Chr. 1 p36.11
Identifiers
Symbol IL22RA2
Entrez 116379
HUGO 14901
OMIM 606648
RefSeq NM_181310
UniProt Q969J5
Other data
Locus Chr. 6 q24.1-24.2

Interleukin-22 receptor is a type II cytokine receptor. It binds to Interleukin-22. It is a heterodimer of α1[1] and α2[2] subunits.

References

  1. ^ Xie MH, Aggarwal S, Ho WH, Foster J, Zhang Z, Stinson J, Wood WI, Goddard AD, Gurney AL (2000). "Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R". J. Biol. Chem. 275 (40): 31335–9. doi:10.1074/jbc.M005304200. PMID 10875937. 
  2. ^ Xu W, Presnell SR, Parrish-Novak J, Kindsvogel W, Jaspers S, Chen Z, Dillon SR, Gao Z, Gilbert T, Madden K, Schlutsmeyer S, Yao L, Whitmore TE, Chandrasekher Y, Grant FJ, Maurer M, Jelinek L, Storey H, Brender T, Hammond A, Topouzis S, Clegg CH, Foster DC (2001). "A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist". Proc. Natl. Acad. Sci. U.S.A. 98 (17): 9511–6. doi:10.1073/pnas.171303198. PMID 11481447. 

External links


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Transmembrane receptors: immune receptors
Cytokine receptor
Pattern recognition/Toll-like
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