Interleukin-10 receptor

Interleukin-10 receptor
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Interleukin-10_receptor".

content

interleukin 10 receptor, alpha
Identifiers
Symbol	IL10RA
Alt. Symbols	IL10R
Entrez	3587
HUGO	5964
OMIM	146933
RefSeq	NM_001558
UniProt	Q13651
Other data
Locus	Chr. 11 q23

interleukin 10 receptor, beta
Identifiers
Symbol	IL10RB
Alt. Symbols	CRFB4, D21S58, D21S66
Entrez	3588
HUGO	5965
OMIM	123889
RefSeq	NM_000628
UniProt	Q08334
Other data
Locus	Chr. 21 q22.1-22.2

Interleukin-10 receptor is a type II cytokine receptor. It consists of α^[1] and β^[2] subunits.

References

^ Liu Y, Wei SH, Ho AS, de Waal Malefyt R, Moore KW (1994). "Expression cloning and characterization of a human IL-10 receptor". J. Immunol. 152 (4): 1821–9. PMID 8120391.
^ Kotenko SV, Krause CD, Izotova LS, Pollack BP, Wu W, Pestka S (1997). "Identification and functional characterization of a second chain of the interleukin-10 receptor complex". EMBO J. 16 (19): 5894–903. doi:10.1093/emboj/16.19.5894. PMID 9312047.

External links

MeSH Receptors,+Interleukin-10

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v • d • e Transmembrane receptors: immune receptors

Cytokine receptor	Type I: Interleukins (2, 3, 4, 5, 6, 7, 9, 11, 12, 13, 15, 21, 23, 27), CSF receptors (EPO, GM-CSF, G-CSF), GH, prolactin, Oncostatin M,Leukemia inhibitory factor - common subunits (Common gamma chain, common beta chain, CSF2RB) Type II: Interleukins (10, 20, 22, 28) - interferon (-α/β, -γ) immunoglobulin superfamily: CSF1, C-kit, IL-1, IL-18 Tumor necrosis factor: CD27, CD30, CD40, CD120, Lymphotoxin β Chemokines: IL-8 (α, β), CCR1,CXCR4 Other: IL-17, TGF-beta (1, 2)

Pattern recognition/Toll-like	TLR 1 - TLR 2 - TLR 3 - TLR 4 - TLR 5 - TLR 6 - TLR 7 - TLR 8 - TLR 9 - TLR 10

Fc receptor	ε (FcεRI, FcεRII) - γ (FcγRI, FcγRII, FcγRIII) - α/μ (FcαRI, Fcα/μR) - Neonatal

Lymphocyte homing receptor	CD44 - L-selectin - VLA-4 - LFA-1

other	Antigen receptor (B-cell, T cell) - Complement - Formyl peptide - Immunophilins - Integrin - Killer-cell immunoglobulin-like - Scavenger

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