The structure of the liver’s functional units or lobules. Blood enters the lobules through branches of the portal vein and hepatic artery, then flows through sinusoids.
diamond shaped, divided into zone 3, zone 2, zone 1
blood/disease
Sometimes the term "hepatic lobule" only refers to the "classic lobule".
When described as an "acinus lobule", the portal triad (portal vein, artery, bile duct) is at the centre and adjacent two central veins are at the periphery of the lobule. The liver parenchyma would be divided into zones based on oxygen supply. Zone 1 encircles portal tract where oxygen rich blood enters via hepatic arteries where as zone 3 being farthest has poorest oxygenation.