Gliquidone

Gliquidone
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Gliquidone
Systematic (IUPAC) name
3-cyclohexyl-1-[4-[2-(7-methoxy-4,4-dimethyl-1,3- dioxo-isoquinolin-2-yl)ethyl]phenyl]sulfonyl-urea
Identifiers
CAS number	33342-05-1
ATC code	A10BB08
PubChem	91610
Chemical data
Formula	C₂₇H₃₃N₃O₆S
Mol. mass	527.634 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	95% Biliary, 5% Renal
Therapeutic considerations
Pregnancy cat.	?
Legal status	POM(UK)
Routes	Oral

Gliquidone (INN, sold under the trade name Glurenorm) is an anti-diabetic drug in the sulfonylurea class. It is used in the treatment of diabetes mellitus type 2.

v • d • e

Biguanides	Metformin, Buformin^‡, Phenformin^‡

TZDs (PPAR)	Pioglitazone, Rivoglitazone^†, Rosiglitazone, Troglitazone^‡

Sulfonylureas	1st generation: Carbutamide, Chlorpropamide, Gliclazide, Tolbutamide, Tolazamide 2nd generation: Glipizide, Glibenclamide (Glyburide), Gliquidone, Glyclopyramide 3rd generation: Glimepiride

Meglitinides	Nateglinide, Repaglinide, Mitiglinide

Glucagon-like peptide-1 analog	Exenatide, Liraglutide^†, Albiglutide^†, Taspoglutide^†

DPP-4 inhibitors	Alogliptin^†, Linagliptin^†, Saxagliptin^†, Sitagliptin, Vildagliptin

Amylin analog

Dual PPAR agonists	Aleglitazar^†, Muraglitazar^§, Tesaglitazar^§

SGLT2 inhibitor	Dapagliflozin^†, Remogliflozin^†, Sergliflozin^†

^†Undergoing clinical trials. ^‡ Withdrawn from market. ^§Development halted.

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