Ganglionic blocker
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Ganglionic_blocker".

A ganglionic blocker (or ganglioplegic) is a type of medication which inhibits postganglionic transmission,^[1] primarily by acting as a nicotinic antagonist.^[2]

Because ganglonic blockers block the parasympathetic nervous system and sympathetic nervous system, the effect of these drugs depend upon the dominant tone in the organ system. ^[3]

Examples

Examples include hexamethonium, pentolinium, mecamylamine, trimetaphan and pempidine.

Others include:^[4]

• benzohexonium
• chlorisondamine
• pentamine

Uses

Ganglionic blockers are used less frequently now than they were in the past, because more selective agents are now available. However, they are still used in some emergency situations, such as aortic dissection.

References

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.