In anatomy, in the occipital bone, the foramen magnum (Latin: 'great hole') is one of the several oval or circular apertures in the base of the skull (the foramina), through which the medulla oblongata (an extension of the spinal cord) enters and exits the skull vault.
In humans, the foramen magnum is farther underneath the head than in great apes. Thus, in humans, the neck muscles do not need to be as robust in order to hold the head upright. Comparisons of the position of the foramen magnum in early hominid species are useful to determine how comfortable a particular species was when walking on two limbs (bipedality) rather than four.
The foramen magnum is the border line above which is the brain, and below, the spinal cord.
This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained herein may be outdated. Please edit the article if this is the case, and feel free to remove this notice when it is no longer relevant.