There is a large body of modern fiction set in ancient Rome. The following titles listed include only those that are substantially (more than half) or entirely set in the city of Rome during any period up to the Byzantine empire. It does not include works set partially in Rome, nor does it include all works set in the Roman Republic or the Roman Empire. For works set in the Roman empire but not in the city of Rome, please see Fiction set in the Roman empire for a list of all works set in the ancient Roman world.
I, Claudius (1934) and its sequel, Claudius the God (1935), by Robert Graves. The classic and influential dramatised account of the life of the emperor Claudius, made into a popular TV series (see below).
The Caius Trilogy by German author Henry Winterfeld: Caius ist ein Dummkopf (Caius is an Idiot); Caius geht ein Licht auf (Caius has an Inspiration), and Caius in der Klemme (Caius in a Fix). The first part was published in English with the alternate title Detectives in Togas. The second was published in English with the alternate title Mystery of the Roman Ransom.
The Third Princess: A Septimus Severus Quistus Roman Mystery by Philip Boast