Enoyl CoA isomerase This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Enoyl_CoA_isomerase".
Enoyl CoA isomerase (EC 5.3.3.8) is an enzyme that catalyzes conversion of cis-double bonds of fatty acids at position 3 to trans double bonds at position 2. It has a special importance in metabolism of unsaturated fatty acids.
Fatty acid synthesis/Fatty acid synthase: Beta-ketoacyl-ACP synthase - Β-Ketoacyl ACP reductase - 3-Hydroxyacyl ACP dehydrase - Enoyl ACP reductase
Beta oxidation/Mitochondrial trifunctional protein: Acyl CoA dehydrogenase (ACADL, ACADM, ACADS, ACADVL) - Enoyl-CoA hydratase - 3-Hydroxyacyl CoA dehydrogenase - Acetyl-CoA C-acyltransferase
to acetyl-CoA: Malonyl-CoA decarboxylase
unsaturated (Enoyl CoA isomerase, 2,4 Dienoyl-CoA reductase)
odd chain (Propionyl-CoA carboxylase)
