E. coli nitroreductase This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "E._coli_nitroreductase".
E. coli nitroreductase is a flavoprotein found in the bacteria Escherichia coli. It catalyses the reduction of nitro groups in a wide range of substrates, to produce the corresponding hydroxylamine. Although its role in vivo is unclear, it has been identified as useful in the metabolism of a number of prodrugs in anti-cancer gene therapy.1
