Cortés is one of the 18 departments into which the Central American nation of Honduras is divided. The department covers a total surface area of 3,954 km² and, in 2005, had an estimated population of 1,365,497 people, making it the most populous department in Honduras. The Merendón Mountains rise in western Cortés, but the department is mostly a tropical lowland, the Sula Valley, crossed by the Ulúa and Chamelecon rivers.
Cortés is the economic heartland of Honduras, as the Sula Valley is the country's main agricultural and industrial region. US banana companies arrived in the area in the late 19th Century, and established vast plantations, as well as infrastructure to ship the fruit to the United States. San Pedro Sula attracted substantial numbers of European, Central American, and Palestinian and Lebanese immigrants. Industry flourishes in the department, and Cortés today hosts most of the country's assembly plants, known as maquilas.