Cerezyme

Cerezyme
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Cerezyme".

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Imiglucerase
Systematic (IUPAC) name
Human Beta-glucocerebrosidase
Identifiers
CAS number	143003-46-7
ATC code	A16AB02
PubChem	?
DrugBank	BTD00026
Chemical data
Formula	C₂₅₃₂H₃₈₅₄N₆₇₂O₇₁₁S₁₆
Mol. mass	55597.4 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	3.6-10.4 min
Excretion	?
Therapeutic considerations
Licence data	EU, US
Pregnancy cat.	?
Legal status
Routes	Intravenous

Imiglucerase is a recombinant DNA-produced analogue of human β-glucocerebrosidase. Cerezyme is a freeze-dried medicine containing imiglucerase, manufactured by Genzyme Corporation. It is given intravenously after reconstitution as a treatment for Type 1 Gaucher's disease. It is available in formulations containing 200 mg per vial and 400 mg per vial.

v • d • e Other alimentary tract and metabolism products (A16)

Amino acids and derivatives	Levocarnitine - Ademetionine - Levoglutamide - Mercaptamine - Carglumic acid - Betaine

Enzymes	Alglucerase - Imiglucerase - Agalsidase alfa - Agalsidase beta - Laronidase - Sacrosidase - Alglucosidase alfa - Galsulfase - Idursulfase

Various alimentary tract and metabolism products	Tioctic acid - Anethole trithione - Sodium phenylbutyrate - Nitisinone - Zinc acetate - Miglustat

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