CCL4
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "CCL4"
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Chemokine (C-C motif) ligand 4
PDB rendering based on 1hum.
Available structures: 1hum, 1hun, 1je4, 2ffk, 2fin
Identifiers
Symbols CCL4; SCYA2; ACT2; AT744.1; G-26; LAG1; MGC104418; MGC126025; MGC126026; MIP-1-beta; MIP1B; SCYA4
External IDs OMIM: 182284 MGI98261 HomoloGene48153
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 6351 20303
Ensembl ENSG00000129277 ENSMUSG00000018930
Uniprot P13236 Q5QNV9
Refseq NM_002984 (mRNA)
NP_002975 (protein)
NM_013652 (mRNA)
NP_038680 (protein)
Location Chr 17: 31.46 - 31.46 Mb Chr 11: 83.48 - 83.48 Mb
Pubmed search [1] [2]

Chemokine (C-C motif) ligand 4, also known as CCL4, is a human gene.


See also

Further reading

  • Menten P, Wuyts A, Van Damme J (2003). "Macrophage inflammatory protein-1.". Cytokine Growth Factor Rev. 13 (6): 455–81. PMID 12401480. 
  • Muthumani K, Desai BM, Hwang DS, et al. (2004). "HIV-1 Vpr and anti-inflammatory activity.". DNA Cell Biol. 23 (4): 239–47. doi:10.1089/104454904773819824. PMID 15142381. 
  • Conti L, Fantuzzi L, Del Cornò M, et al. (2005). "Immunomodulatory effects of the HIV-1 gp120 protein on antigen presenting cells: implications for AIDS pathogenesis.". Immunobiology 209 (1-2): 99–115. PMID 15481145. 
  • Joseph AM, Kumar M, Mitra D (2005). "Nef: "necessary and enforcing factor" in HIV infection.". Curr. HIV Res. 3 (1): 87–94. PMID 15638726. 
  • Zhao RY, Elder RT (2005). "Viral infections and cell cycle G2/M regulation.". Cell Res. 15 (3): 143–9. doi:10.1038/sj.cr.7290279. PMID 15780175. 
  • Zhao RY, Bukrinsky M, Elder RT (2005). "HIV-1 viral protein R (Vpr) & host cellular responses.". Indian J. Med. Res. 121 (4): 270–86. PMID 15817944. 
  • Li L, Li HS, Pauza CD, et al. (2006). "Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions.". Cell Res. 15 (11-12): 923–34. doi:10.1038/sj.cr.7290370. PMID 16354571. 
  • King JE, Eugenin EA, Buckner CM, Berman JW (2006). "HIV tat and neurotoxicity.". Microbes Infect. 8 (5): 1347–57. doi:10.1016/j.micinf.2005.11.014. PMID 16697675. 
  • Napolitano M, Modi WS, Cevario SJ, et al. (1991). "The gene encoding the Act-2 cytokine. Genomic structure, HTLV-I/Tax responsiveness of 5' upstream sequences, and chromosomal localization.". J. Biol. Chem. 266 (26): 17531–6. PMID 1894635. 
  • Irving SG, Zipfel PF, Balke J, et al. (1990). "Two inflammatory mediator cytokine genes are closely linked and variably amplified on chromosome 17q.". Nucleic Acids Res. 18 (11): 3261–70. PMID 1972563. 
  • Baixeras E, Roman-Roman S, Jitsukawa S, et al. (1991). "Cloning and expression of a lymphocyte activation gene (LAG-1).". Mol. Immunol. 27 (11): 1091–102. PMID 2247088. 
  • Lipes MA, Napolitano M, Jeang KT, et al. (1989). "Identification, cloning, and characterization of an immune activation gene.". Proc. Natl. Acad. Sci. U.S.A. 85 (24): 9704–8. PMID 2462251. 
  • Brown KD, Zurawski SM, Mosmann TR, Zurawski G (1989). "A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes.". J. Immunol. 142 (2): 679–87. PMID 2521353. 
  • Zipfel PF, Balke J, Irving SG, et al. (1989). "Mitogenic activation of human T cells induces two closely related genes which share structural similarities with a new family of secreted factors.". J. Immunol. 142 (5): 1582–90. PMID 2521882. 
  • Chang HC, Reinherz EL (1989). "Isolation and characterization of a cDNA encoding a putative cytokine which is induced by stimulation via the CD2 structure on human T lymphocytes.". Eur. J. Immunol. 19 (6): 1045–51. PMID 2568930. 
  • Miller MD, Hata S, De Waal Malefyt R, Krangel MS (1989). "A novel polypeptide secreted by activated human T lymphocytes.". J. Immunol. 143 (9): 2907–16. PMID 2809212. 
  • Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.". Nature 377 (6547 Suppl): 3–174. PMID 7566098. 
  • Post TW, Bozic CR, Rothenberg ME, et al. (1995). "Molecular characterization of two murine eosinophil beta chemokine receptors.". J. Immunol. 155 (11): 5299–305. PMID 7594543. 
  • Combadiere C, Ahuja SK, Murphy PM (1995). "Cloning and functional expression of a human eosinophil CC chemokine receptor.". J. Biol. Chem. 270 (28): 16491–4. PMID 7622448. 
  • Paolini JF, Willard D, Consler T, et al. (1994). "The chemokines IL-8, monocyte chemoattractant protein-1, and I-309 are monomers at physiologically relevant concentrations.". J. Immunol. 153 (6): 2704–17. PMID 8077676. 
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