BAMBI

BAMBI
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "BAMBI".

content

BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
Identifiers
Symbol	BAMBI
Entrez	25805
HUGO	30251
OMIM	604444
RefSeq	NM_012342
UniProt	Q13145
Other data
Locus	Chr. 10 p12.3-11.2

BMP and Activin membrane bound inhibitor (BAMBI), has a similar extracellular domain as type I receptors in the TGF beta signaling pathway. It lacks an intracellular serine/threonine protein kinase domain and hence is a pseudoreceptor.

External links

MeSH BAMBI+protein,+human

This biochemistry article is a stub. You can help Wikipedia by expanding it.

v • d • e Cell signaling: TGF beta signaling pathway

TGF beta superfamily of ligands	TGF beta family (TGF-β1, TGF-β2, TGF-β3) Bone morphogenetic proteins (BMP2, BMP3, BMP4, BMP5, BMP6, BMP7, BMP8a, BMP8b, BMP10 , BMP15) Growth differentiation factors (GDF1, GDF2, GDF3, GDF5, GDF6, GDF7, Myostatin/GDF8, GDF9, GDF10, GDF11, GDF15) Other (Activin A and B/Inhibin A and B, Anti-müllerian hormone, Nodal)

TGF beta receptors (Activin, BMP)	TGFBR1: Activin type 1 receptors (ACVR1, ACVR1B, ACVR1C) - ACVRL1 - BMPR1 (BMPR1A - BMPR1B) TGFBR2: Activin type 2 receptors (ACVR2A, ACVR2B) - AMHR2 - BMPR2 TGFBR3: betaglycan

Transducers/SMAD	R-SMAD (SMAD1, SMAD2, SMAD3, SMAD5, SMAD9) - I-SMAD (SMAD6, SMAD7) - SMAD4

Ligand inhibitors	Cerberus - Chordin - DAN - Decorin - Follistatin - Gremlin - Lefty - LTBP1 - Noggin - THBS1

Coreceptors	BAMBI - Cripto

Other	SARA

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