B-cell receptor
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "B-cell_receptor".

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B-cell receptors are proteins found on the surface of B cells.1

An association with systemic lupus erythematosus has been suggested.2

There are several different types of B-cell receptors, but an individual B-cell can only produce one. B-cell receptors bind antigens, triggering growth and proliferation of B-cells and production of antigen-specific immunoglobulin. This also results in the production of memory cells, which will proliferate if the body is ever exposed to the antigen again.

A B-cell receptor is better known as an antibody.

See also

References

  1. ^ Barral P, Eckl-Dorna J, Harwood NE, et al (June 2008). "B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo". Proc. Natl. Acad. Sci. U.S.A. 105 (24): 8345–50. doi:10.1073/pnas.0802968105. PMID 18550831. http://www.pnas.org/cgi/pmidlookup?view=long&pmid=18550831. 
  2. ^ Jenks SA, Sanz I (August 2008). "Altered B cell receptor signaling in human systemic lupus erythematosus". Autoimmun Rev. doi:10.1016/j.autrev.2008.07.047. PMID 18723129. http://linkinghub.elsevier.com/retrieve/pii/S1568-9972(08)00160-2. 

External links

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Transmembrane receptors: immune receptors
Cytokine receptor
CSF1 · C-kit · IL-1 · IL-18
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Antigen receptor
B-cell · T cell
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