Ascanio Mayone (? - 1627) was an Napolitan composer. He trained as a pupil of Macque in Naples, and worked at Santissima Annunziata there as organist from 1593 and maestro di cappella from 1621; he was also organist at the royal chapel from 1602. He published madrigals, but his main work is his two volumes of keyboard music, Capricci per sonar (1603, 1609). These contain canzonas, toccatas, variations and arrangements of vocal pieces, many of which are distinctively Baroque rather than sixteenth century in style.
