Apatzingán (in full, Apatzingán de la Constitución) is a city and its surrounding municipality located in the west-central part of the state of Michoacán, Mexico. The city is the fourth-largest in Michoacán (behind Morelia, Uruapan, and Zamora), with a 2005 census population of 93,180 persons. The municipality of Apatzingán has an area of 1,656.67 km² (639.64 sq mi) and reported a population of 115,078.
Currently the city of Apatzingán is overrun by notorious, powerful and wealthy drug trafficking cartels. President Felipe Calderón has made this historic town, which is where the Latin American leaders came to write their first constitution, a top priority in his war on drugs.