Antidopaminergic
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Antidopaminergic".

A dopamine antagonist is a drug which blocks dopamine receptors by receptor antagonism. There are five types of dopamine receptors in the human body; they are found in the brain, peripheral nervous system, blood vessels, and the kidney).

Uses and examples

• Used as atypical antipsychotics (coupled with a serotonin antagonist): clozapine, risperidone, olanzapine, quetiapine, ziprasidone, aripiprazole

• Used as antiemetics: metoclopramide, droperidol, domperidone

• Used as tricyclic antidepressants: amoxapine

Side effects

• parkinsonism - due to effects on the nigrostriatal pathway
• hyperprolactinaemia - due to effects on the tuberoinfundibular pathway
• tardive diskinesia (long term use)

Examples

Other examples include:¹

• acepromazine
• amoxapine
• azaperone
• benperidol
• bromopride
• butaclamol
• chlorpromazine
• chlorprothixene
• clopenthixol
• domperidone
• droperidol
• eticlopride
• flupenthixol
• flupenthixol decanoate
• fluphenazine
• fluspirilene
• haloperidol
• loxapine
• mesoridazine
• methotrimeprazine
• metoclopramide
• nafadotride
• nemonapride
• penfluridol
• perazine
• perphenazine
• pimozide
• prochlorperazine
• promazine
• raclopride
• remoxipride
• risperidone
• spiperone
• spiroxatrine
• stepholidine
• sulpiride
• sultopride
• tetrahydropalmatine
• thiethylperazine
• thioridazine
• thiothixene
• tiapride
• trifluoperazine
• trifluperidol
• triflupromazine
• ziprasidone

References

External links

• MeSH Dopamine+antagonists

This psychoactive drug-related article is a stub. You can help Wikipedia by expanding it.