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Antianalgesia is the ability of some endogenous chemicals (notably cholecystokinin and neuropeptide Y) to counter the effects of exogenous analgesics (such as morphine) or endogenous pain inhibiting neurotransmitters/modulators, such as the endogenous opioids.1 A learned form can be established using methods similar to the learning principle of conditioned inhibition, and has been demonstrated in rats.
References
- ^ Wiertelak, EP; Maier, SF and Watkins, LR (8 May 1992). "Cholecystokinin antianalgesia: safety cues abolish morphine analgesia" (abstract). Science 256 (5058): 830–833. doi:. PMID 1589765, http://www.sciencemag.org/cgi/content/abstract/256/5058/830. Retrieved on 12 February 2007.
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