Albert Frederick (German: Albrecht Friedrich; 7 May 1553 – 28 August 1618) was duke of Prussia from 1568 until his death. He was a son of Albert of Prussia and Anna Marie of Brunswick-Lüneburg. He was the second and last Prussian duke of the Ansbach branch of the Hohenzollern family. He exhibited signs of mental disorder. In early 1578, the regency was taken over by his cousin, Georg Friedrich of Brandenburg-Kulmbach (1539-1603).
At his death, the duchy passed to his son-in-law John Sigismund, Margrave of Brandenburg, combining the two territories under a single dynasty and forming Brandenburg-Prussia.