8-oxoguanine

8-oxoguanine
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "8-oxoguanine".

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8-Oxoguanine^[1]

IUPAC name	2-amino-3H-purine-6,8-dione
Identifiers
CAS number	[82014-86-6]
PubChem	119315
MeSH	8-oxyguanine
SMILES	`C12=NC(=O)N=C1NC(=NC2=O)N`
Properties
Molecular formula	C₅H₃N₅O₂
Molar mass	165.10962
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references

8-Oxo-7,8-dihydroguanine, also 8-oxoguanine, 8-hydroxyguanine, 8-oxo-Gua, or oh⁸Gua, is one of the most common DNA lesions resulting from reactive oxygen species. It is primarily repaired by the DNA glycosylase OGG1. It is caused by ionizing radiation, and is also produced in oxidative metabolism.

References

v • d • e

Nucleobases, nucleosides, and nucleotides

Ribonucleosides	Adenosine \| Guanosine \| Uridine \| Cytidine

Deoxyribonucleosides	Deoxyadenosine \| Deoxyguanosine \| Thymidine \| Deoxyuridine \| Deoxycytidine

Ribonucleotide	monophosphates (AMP, GMP, UMP, CMP) \| diphosphates (ADP, GDP, UDP, CDP) \| triphosphates (ATP, GTP, UTP, CTP)

Deoxyribonucleotides	monophosphates (dAMP, dGMP, dUMP, TMP, dCMP) \| diphosphates (dADP, dGDP, TDP, dCDP) \| triphosphates (dATP, dGTP, TTP, dCTP)

Cyclic	cAMP, cGMP, c-di-GMP, cADPR