In the 44th century, around the year 4380, Comet Hale-Bopp is expected to return to the inner solar system. It last dominated the skies of Earth in 1996–1997.
In the 49th century, The Great Comet of 1811 is expected to return to the inner solar system. According to calculations made at the time, the comet should return around the year 4876.
Astrological events
Sometime during the first eight centuries of the 5th millennium (calculations vary among different astrologers), the 2,158 year long Age of Aquarius will end and the Age of Capricorn will begin.
Fictional events
In the Zager and Evans song, In the Year 2525 — "In the year 4545. Ain't gonna need your teeth, won't need your eyes. You won't find a thing to chew. Nobody's gonna look at you."
The Blasterman universe mainly takes place in the early 4060's.
A majority of the events of David Weber's Honor Harrington novels and short stories take place during the early years of the fifth millennium.
In the film A. I., a sequence said to take place in 4001 features the extinction of mankind after the ocean freezes over, but other intelligent life, the descendants of mankind's early intelligent robots, return to earth and excavate to discover their origins.
49th century: Susan from the television programme Doctor Who is born.
The events of the Doctor Who episode 42 will take place in the 42nd century.
The events of the Doctor Who episode Planet of the Ood take place in the 42nd century, in the year 4126. The Ood are slaves to humans at this point in time.
The novel series Fifth Millennium by Stirling, Wehrstein and Meier is set in this time, chronicling the lives and travels of several connected characters in a 'low magic' fantasy world that emerged after a nuclear war destroyed almost all former civilization on earth.
