5,10-methylenetetrahydrofolate This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "5,10-methylenetetrahydrofolate".
5,10-Methylenetetrahydrofolate (5,10-CH2-THF) is the substrate used by methylenetetrahydrofolate reductase to generate 5-methyltetrahydrofolate. This is a coenzyme used in thymidine biosynthesis by thymidylate synthase (FAD).