October 19 — The Battle of Zama (130 kilometres south-west of Carthage) ends the Second Punic War and largely destroys the power of Carthage. Roman and Numidian forces under the laedership of the Roman general Publius Cornelius Scipio and his Numidian ally, Masinissa, defeat a combined army of Carthaginians and their Numidian allies under the command of Hannibal and forces Carthage to capitulate. Hannibal loses 20,000 men in the defeat, but he is able to escape Masinissa's pursuit.
Roman Republic
Following the Battle of Zama, the Roman general Publius Cornelius Scipio gains the surname "Africanus" in honour of his feats in North Africa against Carthage.
Agathocles' rule provokes Tlepolemus, the governor of Pelusium (Egypt's eastern frontier city), into action. Tlepolemus marches on Alexandria, where his supporters rouse a mob, compelling Agathocles to resign.
The Egyptian boy king, Ptolemy V, is encouraged by a mob clamouring for revenge against the murderers of his mother Arsinoe III to agree to Agathocles being killed. As a result, the mob searches out and butchers Agathocles and his family. Tlepolemus takes Agathocles’ place as regent. However, he soon proves to be incompetent and is removed.
During this period of confusion and change amongst Egypt’s leadership, armies under the Seleucid king, Antiochus III, make serious inroads into the Egyptian territories in Coele Syria.