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| 1-aminocyclopropane-1-carboxylic acid | |
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| Identifiers | |
| Abbreviations | ACC |
| CAS number | [22059-21-8] |
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| Properties | |
| Molecular formula | C4H7NO2 |
| Molar mass | 101.1 g mol-1 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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1-Aminocyclopropane-1-carboxylic acid (ACC) is a disubstituted cyclic alpha-amino acid in which a three-membered cyclopropane ring is fuzed to the C(alpha)-atom of the amino acid.
ACC plays an important role in the biosynthesis of the plant hormone ethylene.[2][3] It is synthesized by the enzyme ACC synthase ( EC 4.4.1.14) from methionine and converted to ethylene by ACC oxidase (EC 1.14.17.4).[4]
ACC is also a non-physiological partial agonist of the mammalian NMDA receptor.[5]
References
- ^ Caspi R, Foerster H, Fulcher CA, Hopkinson R, Ingraham J, Kaipa P, Krummenacker M, Paley S, Pick J, Rhee SY, Tissier C, Zhang P, Karp PD (2006). "MetaCyc: a multiorganism database of metabolic pathways and enzymes". Nucleic Acids Res. 34 (Database issue): D511–6. doi:. PMID 16381923.
- ^ Yang S, Hoffman N (1984). "Ethylene biosynthesis and its regulation in higher plants". Annu. Rev. Plant Physiol. 35: 155–189. doi:.
- ^ Kende H (1993). "Ethylene biosynthesis". Annu. Rev. Plant Physiol. 44: 283–307. doi:.
- ^ Kende H (1989). "Enzymes of Ethylene Biosynthesis". Plant Physiol. 91 (1): 1–4. PMID 16666977.
- ^ Inanobe A, Furukawa H, Gouaux E (2005). "Mechanism of partial agonist action at the NR1 subunit of NMDA receptors". Neuron 47 (1): 71–84. doi:. PMID 15996549.
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